NDRG Team Reports a Novel System for Monitoring Skeletal Muscle Contraction Employing Magnetic Sensing of 3D engineered muscles
Alec Smith’s work profiled
Alec Smith’s work is profiled in this recent article.
Developing an Integrated Neuromuscular Modeling System| ISCRM (uw.edu)
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UW “New Faculty” Profile for Alec Smith
The University of Washington has featured Alec Smith’s profile in its New Faculty Spotlight.
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Alec Smith awarded NIH R03 grant
Alec Smith has been awarded a two-year R03 grant from NIH entitled Using functional readouts from engineering models of innervated skeletal muscle to assess the efficacy of CRISPR-based c9orf72 ALS gene therapies.
This project is part of a larger effort to employ human induced pluripotent stem cell-derived motor neurons and skeletal muscle to produce in vitro models of the neuromuscular junction to model motor neuron diseases in order to study disease mechanisms and for drug screens.
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David Mack Receives Grant Award
David Mack is the inaugural recipient of a new multi-year award established by Larry and Eileen Tietze for mid-career level scientists. The grant will support efforts to engineer stem cell-derived neuromuscular junctions for the purpose of studying the onset of neuromuscular diseases and testing potential therapeutics.
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New paper from the NDRG team
Samantha Bremner and NDRG co-workers Karen Gaffney, Nathan Sniadecki, and David Mack have published a paper entitled “A Change of Heart: Human Cardiac Tissue Engineering as a Platform for Drug Development” in the journal Current Cardiology Reports.
A Change of Heart: Human Cardiac Tissue Engineering as a Platform for Drug Development
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ISCRM Fellows Awards to Changho Chun, Hunter Furutani, and Cecelia Watson
Three members of the NDRG team; Changho Chun, Hunter Furutani and Cecelia Watson received awards as ISCRM Fellows for fiscal year 2021/2022
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NDRG Attends a Mariners Game
Too bad Mariners hitters are not as productive as NDRG scientists.
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Will Cure Foundation Awards Research Grant to David Mack
David Mack has received a research grant from the Will Cure Foundation to support research concerning gene therapy for X-linked myotubular myopathy.
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ISCRM Innovation Pilot Award to Alec Smith
Alec Smith has been awarded an Innovation Pilot Award by ISCRM. This Washington-State-funded one year grant will fund research into the effect of Duchenne muscular dystrophy on muscle spindles, the sensory receptor structures within skeletal muscle that allow us to sense the extent and speed of contraction of our muscles to permit coordinated movement.
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