Alec Smith awarded NIH R03 grant

Alec Smith has been awarded a two-year R03 grant from NIH entitled Using functional readouts from engineering models of innervated skeletal muscle to assess the efficacy of CRISPR-based c9orf72 ALS gene therapies.

This project is part of a larger effort to employ human induced pluripotent stem cell-derived motor neurons and skeletal muscle to produce in vitro models of the neuromuscular junction to model motor neuron diseases in order to study disease mechanisms and for drug screens.

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ISCRM Innovation Pilot Award to Alec Smith

Alec Smith has been awarded an Innovation Pilot Award by ISCRM. This Washington-State-funded one year grant will fund research into the effect of Duchenne muscular dystrophy on muscle spindles, the sensory receptor structures within skeletal muscle that allow us to sense the extent and speed of contraction of our muscles to permit coordinated movement.

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Changho Chun awarded ISCRM Fellows predoctoral trainee position.

Today Changho Chun was informed that he has been awarded a predoctoral trainee position from the ISCRM Fellows program. The traineeship will support his work developing improved methods for producing induced pluripotent stem cell-based in vitro models of human ventral spinal cord, to be used for study of motor neuron diseases.

Changho Chun awarded ISCRM Fellows predoctoral trainee position. Read More »